Pipeline

Blood and Liquid Cancer

ICTCAR003

Target: CD19

Indication: B-ALL

Pre-clinical Clinical Ind
Pre-clinical Phase complete
Clinical Phase complete
Ind Phase in progress

Clinical trial initiation expected 1Q19

ICTCAR014

Target: CD19 + PD1

Indication: NHL

Pre-clinical Clinical Ind
Pre-clinical Phase complete
Clinical Phase in progress
Ind Phase not started

IND Submission to US FDA expected 1H19; clinical trial initiation expected 2Q19

Solid Tumor

ICTCAR023

Target: TSHR

Indication: Thyroid cancer

Pre-clinical Clinical Ind
Pre-clinical Phase complete
Clinical Phase in progress
Ind Phase not started

Investigator-initiated trials ongoing; top-line data expected 1Q19

ICTCAR043

Target: MUC1

Indication: Breast cancer

Pre-clinical Clinical Ind
Pre-clinical Phase complete
Clinical Phase in progress
Ind Phase not started

Investigator-initiated trials ongoing; top-line data expected 1Q19

ICTCAR046

Target: MUC1

Indication: Pancreatic cancer

Pre-clinical Clinical Ind
Pre-clinical Phase complete
Clinical Phase in progress
Ind Phase not started

Investigator-initiated trials ongoing; top-line data expected 1Q19

ICTCAR049

Indication: Prostate cancer

Pre-clinical Clinical Ind
Pre-clinical Phase in progress
Clinical Phase not started
Ind Phase not started

ICTCAR050

Indication: Urothelial cancer

Pre-clinical Clinical Ind
Pre-clinical Phase in progress
Clinical Phase not started
Ind Phase not started